• Well-Arranged Hotel Front Desk
RESERVATION
Select check-in date close
Select check-out date close

Contact us At Comfort Inn & Suites Santee, SC

As the most responsive Santee hotel near Santee Wildlife Refuge, contacting us is no problem. We provide this page so you never have any problems reserving with us or getting any assistance you need. As you may have found from previous travel, hotels in Santee, South Carolina aren’t all the same. But you can depend on an excellent amenity-rich and convenient experience when you stay in affordable comfort with us. Others may be able meet some of your needs, but we want to meet all your travel needs in this area and exceed your expectations too. May we be of service?

Comfort Inn & Suites

221 Britain Street, Santee, South Carolina 29142, US

+1 (623) 209-7602
+1 (803) 854-4305